Poly-L-lactic acid injections in sagging body skin

Poly-L-lactic acid injections in sagging body skin

Introduction: The treatment of sagging skin in body areas is still a big challenge, as there are few aesthetic procedures aiming to improve it. The poly-L-lactic acid (PLLA) is an injectable synthetic polymer of the alpha-hydroxy acids family, which injection into the deep dermis or superficial hypodermis induces a local and gradual reaction, with synthesis of new collagen by the fibroblasts an...

Fabrication and surface modification of macroporous poly(L-lactic acid) and poly(L-lactic-co-glycolic acid) (70/30) cell scaffolds for human skin fibroblast cell culture.

The fabrication and surface modification of a porous cell scaffold are very important in tissue engineering. Of most concern are high-density cell seeding, nutrient and oxygen supply, and cell affinity. In the present study, poly(L-lactic acid) and poly(L-lactic-co-glycolic acid) (70/30) cell scaffolds with different pore structures were fabricated. An improved method based on Archimedes' Princ...

Skeletal Stability After Mandibular Setback Surgery: Comparisons Among Unsintered Hydroxyapatite/Poly-L-Lactic Acid Plate, Poly-L-Lactic Acid

Purpose: The purpose of this study is to compare the time-course changes in condylar long axis and skeletal stability after sagittal split ramus osteotomy (SSRO) with unsintered hydroxyapatite (u-HA) / poly-L-lactic acid (PLLA) plate, PLLA plate versus titanium plate. Patients and Methods: Of 60 Japanese patients diagnosed of mandibular prognathism, 20 underwent SSRO with u-HA/PLLA plate system...

Apatite-forming ability of bioactive poly(l-lactic acid)/grafted silica nanocomposites in simulated body fluid.

Bioactive PLLA/surface-grafted silica (g-SiO₂) nanocomposite scaffolds were fabricated by solid-liquid phase separation method. And solid PLLA/g-SiO₂ nanocomposite films were prepared by solution casting method. A series of parallel tube-like morphology and internal ladder-like structure of PLLA/g-SiO₂ nanocomposite scaffolds were observed by SEM. The formation of bone-like apatite in the simul...

Cosmetic use of poly-L-Lactic acid for skin rejuvenation: new indications